Anti-Phospho-MAP3K7-S412 Antibody

Phospho-MAP3K7-S412 Polyclonal Antibody
As low as $211.00
In stock
Only %1 left

Product Description


Size 50 ul, 100 ul, 200 ul
Species Human
Host Species Rabbit
Isotype Igg
Buffers 50% glycerol, PBS with 0.02% sodium azide, pH7.3.
Protein Name / Synonyms MAP3K7, CSCF, FMD2, MEKK7, TAK1, TGF1a, mitogen-activated protein kinase kinase kinase 7
Accession Number O43318
Gene Symbols MAP3K7
Gene Id 6885
Purity Affinity purification


The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.


WB 1:500 - 1:2000


Calculated MW
Observed MW


A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7


Phospho S412




Western blot analysis of extracts of K-562 cells, using Phospho-MAP3K7-S412 antibody (144-50071) at 1:1000 dilution. K562 cells were treated by 10% FBS for 30 minutes after serum-starvation overnight or treated by PMA/TPA (200nM).
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.
Western blot - Phospho-MAP3K7-S412 antibody (144-50071)

12 months from the date of shipment when stored properly.
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