PHOX2B Polyclonal Antibody
As low as $166.00
In stock
Only %1 left

Product Description


Size 50 ul, 100 ul, 200 ul
Species Human, Mouse, Rat
Host Species Rabbit
Clonality Polyclonal
Isotype Igg
Buffers 50% glycerol, PBS with 0.02% sodium azide, pH7.3.
Protein Name / Synonyms PHOX2B, NBLST2, NBPhox, PMX2B, paired like homeobox 2b
Accession Number Q99453
Gene Symbols PHOX2B
Gene Id 8929
Purity Affinity purification


The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.


WB 1:500 - 1:2000
IHC 1:50 - 1:200


Calculated MW
Observed MW


Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PHOX2B (NP_003915.2).






Western blot analysis of extracts of various cell lines, using PHOX2B antibody (144-09685) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Western blot - PHOX2B antibody (144-09685)

Immunohistochemistry of paraffin-embedded rat liver using PHOX2B antibody (144-09685) at dilution of 1:100 (40x lens).
Immunohistochemistry - PHOX2B antibody (144-09685)

Immunohistochemistry of paraffin-embedded rat kidney using PHOX2B antibody (144-09685) at dilution of 1:100 (40x lens).
Immunohistochemistry - PHOX2B antibody (144-09685)

12 months from the date of shipment when stored properly.
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