Rabbit Anti-PKM1 (C-term L398) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P14618 |
| Gene Id | 5315 |
| Gene Symbols | PKM |
| Protein Name / Synonyms | PKM1 (C-term L398) |
| Clonality | Polyclonal |
| Preparation | This PKM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-417 amino acids from the C-terminal region of human PKM1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PKM1 is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. The protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Specificity
Other Names
Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; Pyruvate kinase 2/3; Cytosolic thyroid hormone-binding protein; CTHBP; THBP1 ; PKM; PK3; PK2;OIP3
NCBI Accession #
NP_001193725.1;NP_001193726.1;NP_001193727.1;NP_001193728.1;NP_002645.3;NP_872270.1;NP_872271.1
Other Accession #
P14618-2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
57937
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of PKM1 antibody (C-term L398)(Cat# 102-17377) in Hela cell line lysates (35ug/lane). PKM1 (arrow) was detected using the purified Pab. |
 | Western blot analysis of PKM1 antibody (C-term L398) (Cat# 102-17377) in mouse testis tissue lysates (35ug/lane). PKM1 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with PKM1 Antibody (C-term L398), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.