The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.

WB 1:500 - 1:2000

A synthetic peptide corresponding to a sequence within amino acids 550-650 of human PLA2G6 (NP_003551.2).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.