Rabbit Anti-PML Sumoylation Site Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P29590 |
| Gene Id | 5371 |
| Gene Symbols | PML |
| Protein Name / Synonyms | Protein PML, Promyelocytic leukemia protein, RING finger protein 71, Tripartite motif-containing protein 19, PML, MYL, PP8675, RNF71, TRIM19 |
| Clonality | Polyclonal |
| Clone | RB2570 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, IHC-P, IF, FC |
| Research Area | Angiogenesis, Post-Translational Modifications |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).
Other Information
NCBI Accession #
NP_002666.1;NP_150241.2;NP_150242.1;NP_150243.2;NP_150247.2;NP_150249.1;NP_150250.2;NP_150252.1;NP_150253.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
97551
Antigen Source
Human
Images
WB (1:1000)
Western blot analysis of anti-PML Sumoylation Site Antibody (Cat. 102-25400) in Hela cell line lysates (35ug/lane). PML (arrow) was detected using the purified Pab.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.