Rabbit Anti-PON2 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q15165 |
| Gene Id | 5445 |
| Gene Symbols | PON2 |
| Protein Name / Synonyms | PON2 (Center) |
| Clonality | Polyclonal |
| Preparation | This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-101 amino acids from the Central region of human PON2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PON2 is a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.
Specificity
Other Names
PON2; Serum paraoxonase/arylesterase 2; Aromatic esterase 2; Serum aryldialkylphosphatase 2
NCBI Accession #
NP_000296.2
Other Accession #
NP_000296.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39397
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | PON2 Antibody (Center) (Cat# 102-16574) western blot analysis in HepG2 cell line lysates (15ug/lane).This demonstrates the PON2 antibody detected PON2 protein (arrow). |
 | PON2 Antibody (Center) (Cat# 102-16574) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PON2 antibody detected PON2 protein (arrow). |
 | PON2 antibody(Center) (Cat# 102-16574) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PON2 antibody(Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of PON2 Antibody (Center)(Cat# 102-16574) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.