S100A12 Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P80511 |
| Gene Id | 6283 |
| Gene Symbols | S100A12 |
| Protein Name / Synonyms | S100A12, CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6, protein S100-A12 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IHC 1:50 - 1:200
Format
Calculated MW
10kDa
Observed MW
Refer to figures
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12 (NP_005612.1).
Modification
Unmodified
Storage
-20°C
Images
Immunohistochemistry of paraffin-embedded human liver injury using S100A12 antibody (144-05328) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using S100A12 antibody (144-05328) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.