The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human SGCD (NP_000328.2).

Unmodified

-20°C