SIGMAR1 Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q99720 |
| Gene Id | 10280 |
| Gene Symbols | SIGMAR1 |
| Protein Name / Synonyms | SIGMAR1, ALS16, DSMA2, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R, sigma non-opioid intracellular receptor 1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Dilutions
WB 1:500 - 1:2000
IHC 1:100 - 1:200
IHC 1:100 - 1:200
Format
Calculated MW
11kDa/21kDa/22kDa/25kDa
Observed MW
25kDa
Immunogen
Recombinant protein of human SIGMAR1
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using SIGMAR1 antibody (144-05479) at 1:500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Immunohistochemistry of paraffin-embedded mouse kidney using SIGMAR1 antibody (144-05479) (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using SIGMAR1 antibody (144-05479) (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using SIGMAR1 antibody (144-05479) (40x lens).
Expiration:
12 months from the date of shipment when stored properly.