This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.

WB 1:500 - 1:2000; IF 1:50 - 1:200

Recombinant fusion protein containing a sequence corresponding to amino acids 430-524 of human SLC1A1 (NP_004161.4).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.