TMEM43 Polyclonal Antibody
As low as $166.00
In stock
Only %1 left
Code:
144-08509
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Product Description

Specifications

Size 50 ul, 100 ul, 200 ul
Species Human, Mouse
Host Species Rabbit
Clonality Polyclonal
Isotype Igg
Buffers 50% glycerol, PBS with 0.02% sodium azide, pH7.3.
Protein Name / Synonyms TMEM43, ARVC5, ARVD5, EDMD7, LUMA, transmembrane protein 43
Accession Number Q9BTV4
Gene Symbols TMEM43
Gene Id 79188
Purity Affinity purification

Background

This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:100

Format

Calculated MW
44kDa
Observed MW
45kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 80-310 of human TMEM43 (NP_077310.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using TMEM43 antibody (144-08509) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 5s.
Western blot - TMEM43 antibody (144-08509)

Immunohistochemistry of paraffin-embedded human stomach using TMEM43 antibody (144-08509) at dilution of 1:100 (40x lens).
Immunohistochemistry - TMEM43 antibody (144-08509)

Expiration:
12 months from the date of shipment when stored properly.
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