TNFRSF10A Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O00220 |
| Gene Id | 8797 |
| Gene Symbols | TNFRSF10A |
| Protein Name / Synonyms | TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1, TNF receptor superfamily member 10a |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Dilutions
WB 1:200 - 1:500
IHC 1:50 - 1:100
IHC 1:50 - 1:100
Format
Calculated MW
50kDa
Observed MW
45kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 269-468 of human TNFRSF10A (NP_003835.3).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of DU145 cells, using TNFRSF10A antibody (144-06267) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
Immunohistochemistry of paraffin-embedded human stomach using TNFRSF10A antibody (144-06267) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using TNFRSF10A antibody (144-06267) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.