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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P30085 |
| Gene Id | 51727 |
| Gene Symbols | CMPK1 |
| Protein Name / Synonyms | UCK (N-term) |
| Clonality | Polyclonal |
| Preparation | This UCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human UCK. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. This enzyme does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Of note, UCK1 is able to use either ATP or GTP as a phosphate donor. UCK1 also possesses the ability to phosphorylate a number of cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
Specificity
Predicted Reactivity
Rat, Bovine, Pig
Other Names
CMPK1; CMK; CMPK; UCK; UMK; UMPK; UMP-CMP kinase; Cytidine monophosphate kinase; Cytidylate kinase; Deoxycytidylate kinase; Uridine monophosphate kinase; Uridine monophosphate/cytidine monophosphate kinase
NCBI Accession #
NP_001129612.1;NP_057392.1
Other Accession #
Q4KM73; Q29561; Q9DBP5; Q2KIW9
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22222
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-UCK Pab (Cat# 102-17813) is used in Western blot to detect UCK in mouse cerebellum tissue lysate (Lane 1) and HepG2 cell lysate (Lane 2). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.