Rabbit Anti-VINC (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P18206 |
| Gene Id | 7414 |
| Gene Symbols | VCL |
| Protein Name / Synonyms | VINC (N-term) |
| Clonality | Polyclonal |
| Preparation | This VINC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human VINC. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.
Specificity
Predicted Reactivity
Rat, Chicken, Pig
Other Names
VCL; Vinculin; Metavinculin
NCBI Accession #
NP_003364.1;NP_054706.1
Other Accession #
P85972; P26234; Q64727; P12003
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
123799
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-VINC Antibody (N-term) (Cat# 102-17341) in K562 cell line lysates (35ug/lane). VINC (arrow) was detected using the purified Pab. |
 | Western blot analysis of anti-VINC Antibody (N-term) (Cat# 102-17341) in mouse lung tissue lysates (35ug/lane). VINC (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with VINC antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.