Rabbit Anti-ZRANB1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9UGI0 |
| Gene Id | 54764 |
| Gene Symbols | ZRANB1 |
| Protein Name / Synonyms | ZRANB1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
Specificity
Predicted Reactivity
Bovine
Other Names
ZRANB1; TRABID; Ubiquitin thioesterase ZRANB1; TRAF-binding domain-containing protein; Zinc finger Ran-binding domain-containing protein 1
NCBI Accession #
NP_060050.2
Other Accession #
Q7M760; A6QP16
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
80967
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of ZRANB1 Antibody (C-term) (Cat# 102-18411) in K562 cell line lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab. |
 | Western blot analysis of ZRANB1 Antibody (C-term) (Cat# 102-18411) in mouse cerebellum tissue lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab. |
 | ZRANB1 Antibody (C-term) (Cat# 102-18411) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZRANB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.