Protein Name & Synonyms:
JAM-1 / CD321
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
Concentration (lot specific):
IgG concentration 1.0 mg/ml
This product recognizes murine CD321, which is also known as junctional adhesion molecule 1 (JAM-1). CD321 is a 32-41kD glycoprotein, which shares similarities with related proteins JAM-2 and JAM-3.
CD321 is a multifunctional protein that is primarily expressed by platelets, endothelial and epithelial cells. The CD321 protein co-localises with tight junction molecules in both epithelial and endothelial cells and plays an important role in the regulation of junctional integrity and permeability. In addition, CD321 is a ligand for the integrin LFA-1 and is also involved in the transmigration of leucocytes.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
MTE1/MTE2 stromal cell lines.
Cells from immunised Lou rats were fused with cells of the X63 mouse myeloma cell line.
12 months from the date of shipment when stored properly.