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Recombinant Human GALECTIN-1
Catalog #: DS-01-0504
Purified recombinant galectin-1 expressed in E.coli
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Protein Name / Synonyms | GALECTIN-1, |
| Purity | >98% by SDS PAGE/HPLC analysis |
| Molecular Weight (kDa) | 14.5kD (134 amino acid residues) |
| Format | Purified recombinant protein - lyophilized |
| Formulation | 10mM Sodium phosphate pH7.5 |
| Concentration (lot specific) | Total protein concentration ~0.1 mg/ml after reconstitution |
| Preservative | None present |
| Activity | Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µ,g/ml with a peak response obtained at 250 µ,g/ml. |
| Recommended Applications | ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane), ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane) |
| Endotoxin Level | < 1 EU/ug |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Human galectin-1 (Gal-1) is a member of the galectin family of beta-galactoside-binding proteins, which exhibits both intracellular and extracellular functions, and is differentially expressed by a wide range of normal and neoplastic tissues.
Galectin-1 has been implicated in several major cellular functions including proliferation, motility, haematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of Gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and studies have shown the importance of Gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.
Galectin-1 has been implicated in several major cellular functions including proliferation, motility, haematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of Gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and studies have shown the importance of Gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.
Specifications
Size
50 ug
Stability & Storage
Storage/Stability
Prior to reconstitution store at +4°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.