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Recombinant Human GALECTIN-3
Catalog #: DS-01-0505
Purified recombinant galectin-3 expressed in E.coli
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Protein Name / Synonyms | GALECTIN-3, |
| Purity | >98% by SDS PAGE/HPLC analysis |
| Molecular Weight (kDa) | 26.0kD (250 amino acid residues) |
| Format | Purified recombinant protein - lyophilized |
| Concentration (lot specific) | Total protein concentration ~0.1 mg/ml after reconstitution |
| Preservative | None present |
| Activity | Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µ,g/ml with a peak response obtained at 250 µ,g/ml. |
| Recommended Applications | ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane), ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane) |
| Endotoxin Level | < 1 EU/ug |
| Research Area | Cardiovascular Disease |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Galectin-3 (Gal-3) is a member of the galectin family of beta-galactoside-binding proteins, which is involved in both intracellular and extracellular functions and exhibits anti-apoptotic properties.
Gal-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Gal-3 acts as a regulator of tumour metastasis, and several studies have shown a correlation between levels of Gal-3 and tumour progression in liver, thyroid, colon, gastric and breast carcinomas, making Gal-3 an emerging cancer marker.
Gal-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Gal-3 acts as a regulator of tumour metastasis, and several studies have shown a correlation between levels of Gal-3 and tumour progression in liver, thyroid, colon, gastric and breast carcinomas, making Gal-3 an emerging cancer marker.
Specifications
Size
50 ug
Assay Buffers
Phosphate buffered saline
Stability & Storage
Storage/Stability
Prior to reconstitution store at +4°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.