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ISO 13485:2016 cGMP
Recombinant Human RESISTIN
Catalog #: 229-20191
Purified recombinant resistin expressed in E.coli.
Product Description
Specifications
| Size | 25 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Protein Name / Synonyms | RESISTIN, |
| Purity | >98% by SDS PAGE and HPLC analysis. |
| Molecular Weight (kDa) | 19.5kD |
| Format | Purified recombinant protein - lyophilized |
| Formulation | 10mM Sodium Citrate |
| Concentration (lot specific) | Total protein concentration ~0.1mg/ml after reconstitution |
| Preservative | None present |
| Activity | Determined by its ability to stimulate lipolysis in cultured human adipocytes. |
| Recommended Applications | ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane), ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane) |
| Endotoxin Level | <1EU/ug |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Introduction
Human resistin, a disulfide-linked homodimeric protein otherwise known as adipose tissue-specific secretory factor, is an adipose-derived hormone and member of the resistin/FIZZ family, implicated as a suppressor of the ability of insulin to reduce blood sugar, and to play a role in type 2 diabetes and obesity.
Studies have shown that resistin is involved in an increase in the transcription/expression of many pro-inflammatory cytokines, including interleukin-1,-6 and -12, and also upregulates vascular cell-adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), and monocyte chemotactic protein-1 (MCP-1/CCL2).
Studies have shown that resistin is involved in an increase in the transcription/expression of many pro-inflammatory cytokines, including interleukin-1,-6 and -12, and also upregulates vascular cell-adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), and monocyte chemotactic protein-1 (MCP-1/CCL2).
Specifications
Size
25 ug
Stability & Storage
Storage/Stability
Prior to reconstitution store at +4°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.