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Sonic HedgeHog, Human Recombinant

Catalog #: 228-12107

Product Description

Specifications

Size25 µg, 1000 µg
Estimated Lead Time2-3 weeks
SpeciesHuman
Accession Number
Q15465
Gene Id
6469
Protein Name / Synonyms
SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5.
Expressed Region
MIIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKISRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRALDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGGCFP
Expression SystemE. coli
Purity
Greater than 97.0% as determined by SDS-PAGE.
Format
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
SHH is lyophilized from 10mM Na3PO4, pH 7.5.
Activity
The activity is measured by the dose-dependent induction of alkaline phosphatase production by C3H/10T1/2 (CCL-226) fibroblasts and is 1.2-1.8ug/ml corresponding to a specific activity of 800U/mg.
Research AreaCardiovascular Disease
Shipping TypeAmbient temperature
Storage-20°C

Description

Description

Sonic HedgeHog Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 20.1kDa. The Cys at position 2 has been substituted with 2 Ile's. 

Stability & Storage

Storage/Stability
Lyophilized Human Sonic HedgeHog although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Sonic HedgeHog should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.