Rabbit anti-Apolipoprotein Recombinant Monoclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P02654 |
| Gene Id | 341 |
| Gene Symbols | APOC1 |
| Protein Name / Synonyms | APOC1, Apo-CI, ApoC-I, apo-CIB, apoC-IB, Apolipoprotein C1 |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human APOC1 (Catalog #: 144-65952). |
| Isotype | IgG |
| Purification | Affinity purification |
| Molecular Weight (kDa) | 9 kDa |
| Buffers | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH 7.3. |
| Recommended Applications | WB, IHC-P, IF/ICC, ELISA |
| Research Area | Glycolysis & Lipid Metabolism |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Typical Data
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25 μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Exposure time: 180s.
Dilutions
IHC 1:50 - 1:100; IHC-P 1:50 - 1:200; IF/ICC 1:50 - 1:200
Storage/Stability
Store at -20°C. Avoid freeze / thaw cycles.
Expiration
12 months from the date of shipment when stored properly.