CES2 Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O00748 |
| Gene Id | 8824 |
| Gene Symbols | CES2 |
| Protein Name / Synonyms | CES2, CE-2, CES2A1, PCE-2, iCE, cocaine esterase |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
Format
Calculated MW
59kDa/61kDa
Observed MW
62kDa
Immunogen
A synthetic peptide of human CES2
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using CES2 antibody (144-01514) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded human colon using CES2 antibody (144-01514) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of MCF-7 cells using CES2 antibody (144-01514). Blue: DAPI for nuclear staining.
Expiration:
12 months from the date of shipment when stored properly.