HTRA2 Polyclonal Antibody
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | O43464 |
| Gene Id | 27429 |
| Gene Symbols | HTRA2 |
| Protein Name / Synonyms | HTRA2, MGCA8, OMI, PARK13, PRSS25, HtrA serine peptidase 2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IP |
| Research Area | Apoptosis, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:50 - 1:100
IHC 1:50 - 1:200
IP 1:50 - 1:100
Format
Calculated MW
38kDa/39kDa/46kDa/48kDa
Observed MW
Refer to figures
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 334-458 of human HTRA2 (NP_037379.1).
Modification
Unmodified
Storage
-20°C
Images
Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug HTRA2 antibody (144-60834). Western blot was performed from the immunoprecipitate using HTRA2 antibody (144-60834) at a dilition of 1:1000.
Expiration:
12 months from the date of shipment when stored properly.