Human CD95 Antibody [clone: huFasM38], monoclonal mouse IgG1. Validated for flow cytometry.
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Product Description
Specifications
| Size | 25 tests, 100 tests |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P25445 |
| Gene Id | 355 |
| Gene Symbols | FAS, APT1, FAS1, TNFRSF6 |
| Protein Name / Synonyms | Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95) |
| Clonality | Monoclonal |
| Clone | huFasM38 |
| Conjugation | RayBright® Red 647 |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG1 |
| Format | Liquid |
| Concentration (lot specific) | 5 μl/test |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Apoptosis, Cardiovascular Disease, Autoimmune Disease |
| Excitation Laser | Red Laser, 633 nm |
| Maximum Emission Wavelength | 664 nm, replace Cy5™ and Alexa Fluor™ 647 (Cy5™ and Alexa Fluor™ are the trademark of Invitrogen and GE Health Care) |
| Shipping Type | Blue ice |
| Storage | 4°C |
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Typical Data
Human PBMCs were stained with RayBright® Red 647 Anti-Human CD95 antibody (#136-24073, solid line), or mouse IgG isotype control (dashed line).
Description
CD95 is a single chain type I glycoprotein in the TNF receptor superfamily which is expresed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. When activation takes place, CD95 is upregulated. When the extracellular region of CD95 binds to the Fas ligand (CD178) apoptosis is induced.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.
