GUCA2B Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q16661 |
| Gene Id | 2981 |
| Gene Symbols | GUCA2B |
| Protein Name / Synonyms | GUCA2B, GCAP-II, UGN, guanylate cyclase activator 2B |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
12kDa
Observed MW
12kDa
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GUCA2B (NP_009033.1).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of mouse small intestine, using GUCA2B antibody (144-08390) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Expiration:
12 months from the date of shipment when stored properly.