Rabbit Anti-TNIK(S764) Antibody, 200 µl
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Product Description
Specifications
| Size | 200 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9UKE5 |
| Gene Id | 23043 |
| Gene Symbols | TNIK |
| Protein Name / Synonyms | TRAF2 and NCK-interacting protein kinase, 2.7.11.1, TNIK, KIAA0551 |
| Clonality | Polyclonal |
| Clone | RB59089 |
| Isotype | IgG |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
Other Information
Antigen Type
Synthesized Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
154943
Antigen Source
Human
Images
WB (1:500)
All lanes : Anti-TNIK(S764) Antibody at 1:500 dilution Lane 1: Human brain tissue lysate Lane 2: Caco2 whole cell lysate Lane 3: U-2 OS whole cell lysate Lane 4: U-251 MG whole cell lysate Lane 5: Mouse brain tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 155 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.