Rabbit Anti-Human AANAT (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16613 |
| Gene Id | 15 |
| Gene Symbols | AANAT |
| Protein Name / Synonyms | AANAT (N-term) |
| Clonality | Polyclonal |
| Preparation | This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
Specificity
Other Names
AANAT; SNAT; Serotonin N-acetyltransferase; Aralkylamine N-acetyltransferase
NCBI Accession #
NP_001079.1;NP_001160051.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23344
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of AANAT Antibody (N-term) (Cat# 102-18334) in Y79 cell line lysates (35ug/lane). AANAT (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.