Anti-ABCC1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P33527
Gene Id	4363
Gene Symbols	ABCC1
Protein Name / Synonyms	ABCC1 (C-term)
Clonality	Polyclonal
Preparation	This ABCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

Specificity

Predicted Reactivity

Mouse, Bovine, Monkey

Other Names

ABCC1; MRP; MRP1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Leukotriene C(4) transporter

NCBI Accession #

NP_004987.2

Other Accession #

O35379; Q864R9; Q8HXQ5

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

171591

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of ABCC1 antibody (C-term) (Cat# 102-16843) in Ramos cell line lysates (35ug/lane). ABCC1 (arrow) was detected using the purified Pab.
	Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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