Anti-ACCN3 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9UHC3
Gene Id	9311
Gene Symbols	ASIC3
Protein Name / Synonyms	ACCN3 (N-term)
Clonality	Polyclonal
Preparation	This ACCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms.

Specificity

Other Names

ASIC3; ACCN3; SLNAC1; TNAC1; Acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; Neuronal amiloride-sensitive cation channel 3; Testis sodium channel 1

NCBI Accession #

NP_004760.1;NP_064717.1;NP_064718.1

Other Accession #

NP_064718.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

58905

Recommended Dilutions

WB: 1:1000

ACCN3 Antibody (N-term) (Cat# 102-14148) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ACCN3 antibody detected the ACCN3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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