Anti-ACE (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P12821
Gene Id	1636
Gene Symbols	ACE
Protein Name / Synonyms	ACE (C-term)
Clonality	Polyclonal
Preparation	This ACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from the C-terminal region of human ACE.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.

Specificity

Other Names

ACE; DCP; DCP1; Angiotensin-converting enzyme; Dipeptidyl carboxypeptidase I; Kininase II; CD_antigen=CD143; Angiotensin-converting enzyme, soluble form

NCBI Accession #

NP_000780.1;NP_001171528.1;NP_690043.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

149715

Recommended Dilutions

WB: 1:1000

Western blot analysis of anti-ACE Antibody (C-term) (Cat# 102-17626) in mouse lung tissue lysates (35ug/lane). ACE (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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