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Anti-Acrp30 Antibody, Biotinylated
Catalog #: 130-10074B-50
Rabbit anti-Acrp30 Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15848 |
| Gene Id | 9370 |
| Gene Symbols | ADIPOQ ACDC ACRP30 APM1 GBP28 |
| Clonality | Polyclonal |
| Immunogen | Immunogen was a synthetic peptide derived from human Acrp30. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1: 80, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Research Area | Neuroscience, Cancer, Inflammation |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Acrp30 (also known as Adiponectin), is a major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, Adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of Adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
The antibody can specifically bind to human Acrp30 with no cross reactivity to unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse or rat Acrp30 was not tested.
Related Products
Rabbit Anti-Adiponectin / Acrp30, C-terminus (cat# DS-PB-00079)RayBio® Human Adiponectin / Acrp30 ELISA Kit (cat# ELH-Adiponectin-001 )RayBio® Adiponectin / Acrp30 EIA Kit (cat# EIA-ACRP-1)
References
- Lihn, A.S. et al. (2005) Adiponectin: action, regulation and association to insulin sensitivity. Obes. Rev. 6: 13-21.
- Trayhurn, P. and Wood, I.S. (2005) Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem. Soc. Trans. 33: 1078-1081.
Expiration:
12 months from the date of shipment when stored properly.