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Anti-Acvr1 (Center) Antibody
Catalog #: 102-12167
Rabbit Anti-Mouse Acvr1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P37172 |
| Gene Id | 11477 |
| Gene Symbols | ACVR1 |
| Protein Name / Synonyms | Acvr1 (Center) |
| Clonality | Polyclonal |
| Preparation | This Mouse Acvr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the Central region of mouse Acvr1. |
| Concentration (lot specific) | 0.320 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.
Specificity
Predicted Reactivity
Rat, Bovine
Other Names
Acvr1; Acvrlk2; Tgfb1; Activin receptor type-1; Activin receptor type I; Serine/threonine-protein kinase receptor R1; TGF-B superfamily receptor type I; TSK-7L
NCBI Accession #
NP_001103674.1;NP_001103675.1;NP_031420.2
Other Accession #
P80201; Q04771; Q28041; NP_031420.2; NP_001103675.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
57226
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Mouse Acvr1 Antibody (Center) (Cat# 102-12167) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Acvr1 antibody detected the Acvr1 protein (arrow). |
 | Western blot analysis of Acvr1 (arrow) using rabbit polyclonal Mouse Acvr1 Antibody (Center) (Cat# 102-12167). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Acvr1 gene. |
 | Mouse Acvr1 Antibody (Center) (Cat# 102-12167) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Acvr1 antibody detected the Acvr1 protein (arrow). |
 | Mouse Acvr1 Antibody (Center) (102-12167)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Acvr1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.