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Anti-Adiponutrin (C-term) Antibody, Biotinylated
Catalog #: RB-08-0033B-50
Rabbit anti-Adiponutrin (C-terminus) Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | NM_025225 |
| Clonality | Polyclonal |
| Immunogen | Immunogen was a synthetic peptide derived from Mouse Adiponutrin. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography. |
| Immunogen Sequence | CLSERAPHLLRDARTFFGD |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1:10 |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Adiponutrin, designated as ADPN is a 53 kDa member of the PNPLA family of phospholipase A2 enzymes. It also is called as PNPLA3, patatin-like phospholipase domain-containing protein 3. ADPN is expressed in white adipocytes. Very importantly, it is a predominantly liver-expressed transmembrane protein with phospholipase activity that is regulated by fasting and feeding. Recent genome-wide association studies identified PNPLA3 to be associated with hepatic fat content and liver function, thus pointing to a possible involvement in the hepatic lipoprotein metabolism. Investigation also demonstrated that adiponutrin could be involved in vesicular targeting and protein transport restricted to the adipocyte function.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
Human Adiponutrin C-Terminus. Cross reactivity with mouse and rat are expected from sequence similarity.
Applications
ELISA (recommended work dilution= 1:10
Expiration:
12 months from the date of shipment when stored properly.