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Anti-ADRA1B (Center) Antibody
Catalog #: 102-18261
Rabbit Anti-Human ADRA1B (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P35368 |
| Gene Id | 147 |
| Gene Symbols | ADRA1B |
| Protein Name / Synonyms | ADRA1B (Center) |
| Clonality | Polyclonal |
| Preparation | This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human ADRA1B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Rabbit
Other Names
ADRA1B; Alpha-1B adrenergic receptor; Alpha-1B adrenoreceptor
NCBI Accession #
NP_000670.1
Other Accession #
P15823; P97717; P43140; O02824; P97718; P35348; P18130
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
56836
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of ADRA1B Antibody (Center) (Cat# 102-18261) in NCI-H460 cell line lysates (35ug/lane). ADRA1B (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human brain with ADRA1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.