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Anti-AKAP5 (Center) Antibody
Catalog #: 102-14167
Rabbit Anti-Human AKAP5 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P24588 |
| Gene Id | 9495 |
| Gene Symbols | AKAP5 |
| Protein Name / Synonyms | AKAP5 (Center) |
| Clonality | Polyclonal |
| Preparation | This AKAP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human AKAP5. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
Specificity
Other Names
AKAP5; AKAP79; A-kinase anchor protein 5; A-kinase anchor protein 79 kDa; H21; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
NCBI Accession #
NP_004848.3
Other Accession #
NP_004848.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
47088
Recommended Dilutions
WB: 1:1000
 | AKAP5 Antibody (Center) (Cat# 102-14167) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the AKAP5 antibody detected the AKAP5 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.