Rabbit Anti-Human AKR1C3 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P42330 |
| Gene Id | 8644 |
| Gene Symbols | AKR1C3 |
| Protein Name / Synonyms | AKR1C3 (N-term) |
| Clonality | Polyclonal |
| Preparation | This AKR1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKR1C3. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Specificity
Other Names
AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS; Aldo-keto reductase family 1 member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase; Prostaglandin F synthase; Testosterone 17-beta-dehydrogenase 5; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
NCBI Accession #
NP_001240837.1;NP_003730.4
Other Accession #
NP_003730.4
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
36853
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | AKR1C3 Antibody (N-term) (Cat# 102-10572) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AKR1C3 antibody detected the AKR1C3 protein (arrow). |
 | AKR1C3 Antibody (N-term) (Cat# 102-10572) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.