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Anti-AlaRS (AARS) (N-term) Antibody
Catalog #: 102-17417
Rabbit Anti-Human AlaRS (AARS) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49588 |
| Gene Id | 16 |
| Gene Symbols | AARS |
| Protein Name / Synonyms | AlaRS (AARS) (N-term) |
| Clonality | Polyclonal |
| Preparation | This AlaRS (AARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-91 amino acids from the N-terminal region of human AlaRS (AARS). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases,of the class II enzymes.Class II tRNA synthases evolved early in evolution and are highly conserved.This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein.tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons.They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Specificity
Predicted Reactivity
Mouse, Rat, Drosophila, C.Elegans
Other Names
AARS; Alanine--tRNA ligase, cytoplasmic; Alanyl-tRNA synthetase; Renal carcinoma antigen NY-REN-42
NCBI Accession #
NP_001596.2
Other Accession #
Q23122; P50475; Q8BGQ7; Q9VLM8; O01541
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
106810
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-AARS Pab (Cat# 102-17417) in K562 cell line lysates (35ug/lane).AARS (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with AARS antibody (N-term) (Cat# 102-17417), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.