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Anti-ALDH4A1 (Center) Antibody
Catalog #: 102-17676
Rabbit Anti-Human ALDH4A1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P30038 |
| Gene Id | 8659 |
| Gene Symbols | ALDH4A1 |
| Protein Name / Synonyms | ALDH4A1 (Center) |
| Clonality | Polyclonal |
| Preparation | This ALDH4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-314 amino acids from the Central region of human ALDH4A1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
Specificity
Other Names
ALDH4A1; ALDH4; P5CDH; Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 4 member A1
NCBI Accession #
NP_001154976.1;NP_003739.2;NP_733844.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
61719
Recommended Dilutions
IHC: 1:50-100; WB: 1:1000
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH4A1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Western blot analysis of anti-ALDH4A1 Antibody (Center) (Cat# 102-17676) in HepG2 cell line lysates (35ug/lane). ALDH4A1(arrow) was detected using the purified Pab. |
 | Western blot analysis of ALDH4A1 (arrow) using rabbit polyclonal ALDH4A1 Antibody (Center) (Cat# 102-17676). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ALDH4A1 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.