Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P51649 |
| Gene Id | 7915 |
| Gene Symbols | ALDH5A1 |
| Protein Name / Synonyms | ALDH5A1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This ALDH5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-398 amino acids from the C-terminal region of human ALDH5A1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.
Specificity
Predicted Reactivity
Mouse
Other Names
ALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase
NCBI Accession #
NP_001071.1;NP_733936.1
Other Accession #
Q8BWF0
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
57215
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of ALDH5A1 Antibody (C-term) (Cat# 102-12622) in SK-BR-3 cell line lysates (35ug/lane). ALDH5A1(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with *ALDH5A1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.