Anti-ALX4 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9H161
Gene Id	60529
Gene Symbols	ALX4
Protein Name / Synonyms	ALX4 (Center)
Clonality	Polyclonal
Preparation	This ALX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-275 amino acids from the Central region of human ALX4.
Concentration (lot specific)	0.340 mg/ml
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq].

Specificity

Predicted Reactivity

Mouse, Bovine

Other Names

ALX4; KIAA1788; Homeobox protein aristaless-like 4

NCBI Accession #

NP_068745.2

Other Accession #

O35137; Q4LAL6; NP_068745.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

44241

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	ALX4 Antibody (Center) (Cat# 102-10634) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ALX4 antibody detected the ALX4 protein (arrow).
	ALX4 Antibody (Center) (Cat# 102-10634) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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