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Anti-ANPEP/CD13 Antibody
Catalog #: 102-10310
Mouse Anti-Human ANPEP/CD13 Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P15144 |
| Gene Id | 290 |
| Gene Symbols | ANPEP |
| Protein Name / Synonyms | ANPEP/CD13 |
| Clonality | Monoclonal |
| Preparation | This ANPEP/CD13 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from human ANPEP/CD13. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Specificity
Other Names
ANPEP; APN; CD13; PEPN; Aminopeptidase N; Alanyl aminopeptidase; Aminopeptidase M; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; gp150; CD_antigen=CD13
NCBI Accession #
NP_001141.2
Other Accession #
NP_001141.2
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
109540
Recommended Dilutions
WB: 1:100-250
 | ANPEP/CD13 Antibody (Cat# 102-10310) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ANPEP/CD13 antibody detected the ANPEP/CD13 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.