Rabbit Anti-Human APP-Y756 Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P05067 |
| Gene Id | 351 |
| Gene Symbols | APP |
| Protein Name / Synonyms | APP-Y756 |
| Clonality | Polyclonal |
| Preparation | This APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 735-763 amino acids from human APP. |
| Concentration (lot specific) | 0.467 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Specificity
Predicted Reactivity
Mouse, Rat, Pig, Monkey
Other Names
APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; PreA4; Protease nexin-II; N-APP; Soluble APP-alpha; Soluble APP-beta; C99; Beta-amyloid protein 42; Beta-APP42; Beta-amyloid protein 40; Beta-APP40; C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59; Amyloid intracellular domain 59; Gamma-CTF(59); Gamma-secretase C-terminal fragment 57; Amyloid intracellular domain 57; Gamma-CTF(57); Gamma-secretase C-terminal fragment 50; Amyloid intracellular domain 50; Gamma-CTF(50); C31
NCBI Accession #
NP_000475.1;NP_001129488.1;NP_001129601.1;NP_001129602.1;NP_001129603.1;NP_001191230.1;NP_001191231.1;NP_001191232.1;NP_958816.1;NP_958817.1
Other Accession #
P08592; P79307; P12023; P53601
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
86943
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of APP-pY756 (Cat# 102-18126) in T47D cell line lysates (35ug/lane). APP (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.