Rabbit Anti-Human ARHGDIB (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P52566 |
| Gene Id | 397 |
| Gene Symbols | ARHGDIB |
| Protein Name / Synonyms | ARHGDIB (C-term) |
| Clonality | Polyclonal |
| Preparation | This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).
Specificity
Other Names
ARHGDIB; GDIA2; GDID4; RAP1GN1; Rho GDP-dissociation inhibitor 2; Ly-GDI; Rho-GDI beta
NCBI Accession #
NP_001166.3
Other Accession #
NP_001166.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22988
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | ARHGDIB Antibody (C-term) (Cat# 102-12132) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ARHGDIB antibody detected the ARHGDIB protein (arrow). |
 | ARHGDIB Antibody (C-term) (Cat# 102-12132)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ARHGDIB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.