Anti-ASB2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96Q27
Gene Id	51676
Gene Symbols	ASB2
Protein Name / Synonyms	ASB2 (N-term)
Clonality	Polyclonal
Preparation	This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
Concentration (lot specific)	0.380 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Specificity

Other Names

ASB2; Ankyrin repeat and SOCS box protein 2

NCBI Accession #

NP_001189358.1;NP_057234.2

Other Accession #

NP_057234.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

65084

Recommended Dilutions

WB: 1:1000

ASB2 Antibody (N-term) (Cat# 102-13337) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the ASB2 antibody detected the ASB2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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