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Anti-ATF4 (Center) Antibody
Catalog #: 102-11466
Rabbit Anti-Human ATF4 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P18848 |
| Gene Id | 468 |
| Gene Symbols | ATF4 |
| Protein Name / Synonyms | ATF4 (Center) |
| Clonality | Polyclonal |
| Preparation | This ATF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-198 amino acids from the Central region of human ATF4. |
| Concentration (lot specific) | 0.420 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Specificity
Other Names
ATF4; CREB2; TXREB; Cyclic AMP-dependent transcription factor ATF-4; Activating transcription factor 4; Cyclic AMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; Tax-responsive enhancer element-binding protein 67
NCBI Accession #
NP_001666.2;NP_877962.1
Other Accession #
NP_001666.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
38590
Recommended Dilutions
WB: 1:1000
 | ATF4 Antibody (Center) (Cat# 102-11466) western blot analysis in Jurkat,MCF-7 cell line lysates (35ug/lane).This demonstrates the ATF4 antibody detected the ATF4 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.