Anti-ATG9A (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q7Z3C6
Gene Id	79065
Gene Symbols	ATG9A
Protein Name / Synonyms	ATG9A (Center)
Clonality	Polyclonal
Preparation	This ATG9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human ATG9A.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	IHC-P, Western Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

Specificity

Predicted Reactivity

Rat, Bovine

Other Names

ATG9A; APG9L1; Autophagy-related protein 9A; APG9-like 1; mATG9

NCBI Accession #

NP_001070666.1;NP_076990.4

Other Accession #

Q5FWU3; Q68FE2; Q3T904

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

94447

Recommended Dilutions

IHC: 1:50-100; WB: 1:1000

	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
	APG9L1 Antibody (W267) (Cat# 102-13702) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the APG9L1 antibody detected the APG9L1 protein (arrow).
	APG9L1 Antibody (W267) (Cat# 102-13702) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the APG9L1 antibody detected the APG9L1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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