Anti-ATP5A1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P25705
Gene Id	498
Gene Symbols	ATP5A1
Protein Name / Synonyms	ATP5A1 (C-term)
Clonality	Polyclonal
Preparation	This ATP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-503 amino acids from the C-terminal region of human ATP5A1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Pig

Other Names

ATP5A1; ATP5A; ATP5AL2; ATPM; ATP synthase subunit alpha, mitochondrial

NCBI Accession #

NP_001001935.1;NP_001001937.1;NP_001244263.1;NP_001244264.1;NP_004037.1

Other Accession #

P15999; P80021; Q03265; P19483

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

59751

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	ATP5A1 Antibody (C-term) (Cat# 102-18389) western blot analysis in WiDr,NCI-H460,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ATP5A1 antibody detected the ATP5A1 protein (arrow).
	ATP5A1 Antibody (C-term) (Cat# 102-18389) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATP5A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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