Anti-ATP6V1C2 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8NEY4
Gene Id	245973
Gene Symbols	ATP6V1C2
Protein Name / Synonyms	ATP6V1C2 (Center)
Clonality	Polyclonal
Preparation	This ATP6V1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human ATP6V1C2.
Concentration (lot specific)	0.370 mg/ml
Recommended Applications	Western Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.

Specificity

Other Names

ATP6V1C2; V-type proton ATPase subunit C 2; Vacuolar proton pump subunit C 2

NCBI Accession #

NP_001034451.1;NP_653184.2

Other Accession #

NP_653184.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

48759

Recommended Dilutions

WB: 1:1000

ATP6V1C2 Antibody (Center) (Cat# 102-13552) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATP6V1C2 antibody detected the ATP6V1C2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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