Rabbit Anti-Bcl-6 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P41182 |
| Gene Id | 604 |
| Gene Symbols | BCL6 |
| Protein Name / Synonyms | Bcl-6 (C-term) |
| Clonality | Polyclonal |
| Preparation | This Bcl-6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-547 amino acids from the C-terminal region of human Bcl-6. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Apoptosis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
BCL6 is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors.
Specificity
Other Names
BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; B-cell lymphoma 5 protein; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51
NCBI Accession #
NP_001124317.1;NP_001128210.1;NP_001697.2
Other Accession #
P41183
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
78846
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of Bcl-6 Antibody (C-term) (Cat# 102-17310) in mouse cerebellum tissue lysates (35ug/lane). BCL6 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lymph tissue with Bcl-6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Bcl-6 Antibody (C-term) (Cat# 102-17310) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.