Anti-BDK_1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P46663
Gene Id	623
Gene Symbols	BDKRB1
Protein Name / Synonyms	BDK_1 (Center)
Clonality	Polyclonal
Preparation	This BDK_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1.
Concentration (lot specific)	0.430 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

Specificity

Other Names

BDKRB1; BRADYB1; B1 bradykinin receptor

NCBI Accession #

NP_000701.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

40495

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of BDKRB1 Antibody (Center) (Cat# 102-18007) in HepG2 cell line lysates (35ug/lane). BDKRB1 (arrow) was detected using the purified Pab.
	BDKRB1 Antibody (Center) (Cat# 102-18007) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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